Endometrioma affects 17%-44% of women with endometriosis. Approximately 17% of women suffering from infertility are diagnosed with this disease. The pathogenesis of this disease is characterized by sequential and progressive damage of healthy ovarian tissue. During menses, implantation of regurgitated endometrial cells on the ovarian surface (via tubal lumen) causes a series of biochemical mechanisms including persistent inflammation, bleeding (at implantation site) and invagination of the ovarian cortex, adhesions, cystic formations, tissue alterations, and deformity. Read more
Uterine myomas (e.g., leiomyomata, fibroids) are the most common tumor of the reproductive tract, with a cumulative incidence of 70% in women of reproductive age. Fibroids vary greatly in their size, number, and location within the uterus. All factors could negatively impact a woman’s fertility. Regardless of their location, size, or number, uterine fibroids are found in about 5%-10% of women with infertility. For approximately 1.0%-2.4% of women with infertility, uterine fibroids are the only abnormal findings. Read more
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