The Reasons of Fertilization Failure
Why does the fertilization failure sometimes? At the early stage of fertilization, egg and sperm cells are fused, which in the narrow sense is the definition of fertilization. In unfertilized eggs, meiosis ceases at a species-specific stage. The early stage of fertilization breaks the pause in cell division and meiosis resumes. This is called “oocyte activation”. This activation allows meiosis to be completed, and then pronuclei of males and females are formed. The fusion of the male and female genomes (syngamy) completes fertilization in a broad sense. On the other hand, fertilization is not established if fertility of eggs or sperm cells deteriorates. Read more